Three New 2-pyranone Derivatives from Mangrove Endophytic Actinomycete Strain Nocardiopsis sp. A00203

نویسندگان

  • Cheng Lin
  • Chunhua Lu
  • Yuemao Shen
چکیده

Three new 2-pyranone derivatives, namely Norcardiatones A (1), B (2) and C (3), were isolated from the agar cultures of the strain Nocardiopsis sp. A00203, a mangrove endophytic actinomycete. Their structures were elucidated by spectroscopic and mass-spectrometric analyses, including 1D-, 2D-NMR and HR Q-TOFMS. Compound 1 showed week cytotoxicity against HeLa cells in MTT assay.

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تاریخ انتشار 2010